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  1. Hypoadrenocorticism (Addison disease) is an uncommon condition in dogs and even more rare in cats. Hypoadrenocorticism is most often caused by immune-mediated destruction of the adrenal glands resulting in decreased mineralocorticoid and glucocorticoid production.

  2. Addison disease (hypoadrenocorticism), a deficiency in adrenocortical hormones, is seen most commonly in young to middle-aged dogs and occasionally in horses. The disease may be familial in Standard Poodles, West Highland White Terriers, Great Danes, Bearded Collies, Portuguese Water Dogs, and a variety of other breeds.

  3. 9 de feb. de 2018 · Hypoadrenocorticism (HOAC; Addisons disease) is an endocrine condition seen in small animal practice. Dogs with this disease can present in a variety of ways from acute hypovolemic collapse to vague, chronic, waxing, and waning clinical signs.

  4. Canine hypoadrenocorticism, or Addisons disease, results from adrenocortical hormone insufficiency. An overall low disease prevalence combined with vague clinical signs and nonspecific clinicopathologic abnormalities makes diagnosis challenging.

  5. Hypoadrenocorticism (Addisons disease) has been referred to as “the great pretender,” due to its ability to mimic other common diseases in the dog and thereby represent a diagnostic challenge. Naturally occurring hypoadrenocorticism is an uncommon canine disease.

  6. CAUSE. Hypoadrenocorticism is most commonly caused by primary adrenocortical failure involving all three layers of the adrenal cortex (i.e., zona glomerulosa, zona fas-ciculata, zona reticularis).

  7. 31 de ago. de 2018 · Canine hypoadrenocorticism (Addison's disease), the ‘great pretender’ of internal medicine, is a disease that should be frequently considered as a differential diagnosis of several clinical presentations, albeit it is less commonly the actual cause of the clinical signs.