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  1. Hace 3 días · Background Proteasome assembly chaperone 3 (PSMG3), a subunit of proteasome, has been found to be associated with lung cancer. However, the role of PSMG3 in other cancers has not been elucidated. The objective of this study was to explore the immune role of PSMG3 in pan-cancer and confirm the oncogenic significance in liver hepatocellular carcinoma (LIHC). Methods We examined the differential ...

  2. Hace 5 días · (H) Volcano plot showing DEGs between infected and bacterial-negative tumor cells from Zhang2021. For statistics used to determine P values, see Calculation of number of expected infected cells per cell type (10x Genomics protocols) and Calculation of co-infection relationships in colorectal cancer and esophageal cancer datasets subsections of Materials and Methods.

  3. Hace 5 días · c, Volcano plot showing the relationship between MS frameshifts in individual genes and total mutation burden in multiple linear regression analysis. For each independent variable, the P value of ...

  4. Hace 3 días · Ischemic stroke followed by reperfusion (IR) leads to extensive cerebrovascular injury characterized by neuroinflammation and brain cell death. Inhibition of matrix metalloproteinase-3 (MMP-3) emerges as a promising therapeutic approach to mitigate IR-induced stroke injury. We employed middle cerebral artery occlusion with subsequent reperfusion (MCAO/R) to model ischemic stroke in adult mice ...

  5. Hace 3 días · The MIC and MBC values of magnolol against two B. cereus strains (B. cereus ATCC 14579 and B. cereus NCTC 11143) were 2 μg/mL and 4 μg/mL, respectively, while the MIC values of the commercial CAL were even higher at 200 μg/mL, approximately 100-fold higher than that of magnolol, as shown in Table 1.Previous studies have reported on several natural active compounds that exhibit antibacterial ...

  6. Hace 3 días · The ggplot2 package in R software is used to construct a volcano plot of differentially expressed genes (DEGs) for the dataset GSE173097 ... data collection and reference review. Yongping Li provided data analysis and interpretation. Naiyi Du and Wei Zhao wrote and critically revised articles. Yakun Liu had statistical expertise, ...

  7. Hace 4 días · Heatmaps show relationships and changes. A heatmap is an arrangement of rectangles. The x-axis is often some measure of time but can be any variable with groupings. The y-axis is a variable that defines the categories in the data. Each rectangle is the same size, unlike a treemap. The rectangles are colored to show the magnitude of a third ...