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Hace 3 días · Compared to the reported abdominal LD 50-derived (lethal dose for 50%) FLASH effect in Evans et al. of 10-20%, our acute skin TD 50-derived FLASH effect is markedly higher, possibly due to differences in sparing effects across different tissue types . Our ...
Hace 2 días · Lethal median dose and pathogenicity testing. The LD 50 was determined briefly according to the procedure described by Reed and Muench [], briefly.After acclimatization at the wet laboratory of the Animal Health Research Institute, Nile tilapia (n = 10) with a mean weight of (70.8 ± 0.3 g) were anesthetized with 150 µg/ L of tricaine methanesulfonate (MS222; Sigma, St. Louis, MO, the USA ...
Hace 23 horas · This study represents the first application of in silico methods to evaluate the toxicity of 4-methylphenidate (4-Mmph), a new psychoactive substance (NPS). Using advanced in silico toxicology tools, it was feasible to anticipate key aspects of 4-Mmph's toxicological profile, including acute toxicity (LD 50), genotoxicity, cardiotoxicity, and possible endocrine disruption.
Hace 23 horas · Gene expression measurements confirmed target gene silencing and dose–response studies revealed LD 50 values as low as ~20 ng in 14 days following a single exposure to dsRNA. Four highly effective dsRNAs also inhibited leaf damage (up to ~75%) and one affected locomotion.
Hace 2 días · A challenge dose with a lethal dose of 50-70% (LD 50-70) was applied in this challenge study.. Results . The application of EnzActive Protein Powder showed an improved effect on tolerance against AHPND in penaeid juveniles (Penaeus vannamei).Specifically, the survival rate of treatment T1 (EnzActive Protein Powder (0.5g/Kg) was 42.86% higher than that of Positive control as shown in Figure 2.
Hace 4 días · Lysergic acid diethylamide (also known as Lysergide, LSD-25, LSD, L, Lucy, and Acid) is a classical psychedelic substance of the lysergamide class. [2] It is perhaps the most researched and culturally influential psychedelic substance, as well as the prototypal lysergamide.
Hace 3 días · DDT is classified as "moderately toxic" by the U.S. National Toxicology Program (NTP) and "moderately hazardous" by WHO, based on the rat oral LD 50 of 113 mg/kg. Indirect exposure is considered relatively non-toxic for humans.
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