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  1. Charles River provides animal models, including Dunkin-Hartley guinea pigs, for use in basic research and nonclinical drug discovery and development.

  2. The shorthair, albino English or Hartley guinea pig is used commonly in biomedical research, testing, and teaching. Outbred animals are available commercially from many breeders of laboratory animals.

  3. 29 de oct. de 2020 · The Dunkin Hartley guinea pig is an outbred strain that begins developing primary osteoarthritis by 4 months of age with a progression and pathology similar to aging humans.

  4. Guinea pigs. The most reliable small animal model of LF established thus far is the guinea pig. Both the inbred Strain 13 and outbred Hartley guinea pig are susceptible to wild-type (WT) Lassa infection by aerosol, sub cutaneous or intraperitoneal routes ([3, 17, 18]).

  5. 9 de jul. de 2021 · The Dunkin Hartley is the most common guinea pig strain used in biomedical research, particularly for studies of asthma, allergy, infectious disease, reproduction, and osteoarthritis.

  6. 29 de oct. de 2020 · The Dunkin Hartley guinea pig is an outbred strain that begins developing primary osteoarthritis by 4 months of age with a progression and pathology similar to aging humans.

  7. Hartley guinea pigs are the most commonly used guinea pigs for GPCMV studies, but they are less susceptible to infection than the inbred strain 2 guinea pigs that can have high mortality even as adults.