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  1. Plant life developed in the water, and this process took over three billion years. Only relatively recently - speaking in terms of the Earth’s history - when the atmosphere’s oxygen content had reached suitably high levels, terrestrial environments were colonized by plants. The so-called “Step on land” took place about 450 million years ...

  2. Here, we report the isolation of a self-renewing and multipotent human skeletal stem cell (hSSC) that generates progenitors of bone, cartilage, and stroma, but not fat. Self-renewing and multipotent hSSCs are present in fetal and adult bones and can also be derived from BMP2-treated human adipose stroma (B-HAS) and induced pluripotent stem ...

  3. 22 de dic. de 2022 · Naive human pluripotent stem cells (hPSCs) are defined as the in vitro counterpart of the human preimplantation embryo’s epiblast and are used as a model system to study developmental processes. In this study, we report the discovery and characterization of distinct cell populations coexisting with epiblast-like cells in 5iLAF naive human induced PSC (hiPSC) cultures.

  4. Since 2006, the Institute for the Biology of Stem Cells (IBSC) at UC Santa Cruz has supported and worked to advance stem cell research by promoting interdisciplinary discoveries in biology, engineering, and information science. The IBSC has supported over 70 Trainees since its inception in 2005, and aims to continue to do so for many years to ...

  5. 13 de jun. de 2024 · Stem cell biotechnology is important in regenerative medicine. Latest Research and Reviews Forward programming of hiPSCs towards beta-like cells using Ngn3, Pdx1, and MafA

  6. 7 de jun. de 2023 · 4. Research on Stem Cell Therapies: The Long-Term Social Impact. Those familiar with stem cell-based therapies may understand the long and difficult road that precedes a promising discovery at the laboratory level, at which point researchers will seek to translate it to clinical practice in the form of an Advanced Therapeutic Medicinal Product (ATMP).

  7. 14 de jun. de 2019 · Pig intestinal epithelium undergoes a complete renewal every 2 to 3 days that is driven by intestinal stem cells (. ISCs. ) located at. the crypt base in their niche. Intestinal stem cells ...