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  1. Clinically, the disease is characterized as painless, slowly progressive ulcerative lesions on the genitals or perineum without regional lymphadenopathy; subcutaneous granulomas (pseudobuboes) also might occur. The lesions are highly vascular (i.e., beefy red appearance) and can bleed.

  2. The most common cause of a smooth tongue is the use of dentures. Nutritional deficiencies include iron, folate and vitamin B12 deficiency. B12 deficiency will also make the tongue sore and beefy-red in color. Glossitis, by causing swelling of the tongue, may also cause the tongue to appear smooth.

  3. 7 de ago. de 2018 · The “beefy red” patch demonstrated the highest diagnostic validity (Youden index 0.84) and reliability (consistency 91.9% [95% CI: 87.3%–96.5%]), followed by the serum cobalamin levels and MCV.

  4. 29 de dic. de 2023 · Most commonly, donovanosis leads to growth of beefy-red, slow-growing, typically painless ulcers in the genital, groin, and anal area. These ulcers can bleed easily to the touch, and if left untreated, they can spread via lymphatic vessels to surrounding areas, as well as to bone and the liver.

  5. 12 de mar. de 2023 · A non-tender, beefy-red ulcerative lesion that bleeds easily located in or around the genitalia should raise the diagnostic suspicion of granuloma inguinale. The diagnosis is confirmed by identifying Donovan bodies in a tissue smear.

  6. 26 de ago. de 2023 · The skin gradually wears away, and the bumps turn into raised, beefy-red, velvety nodules called granulation tissue. They are often painless, but they bleed easily if injured. The disease slowly spreads and destroys genital tissue.

  7. 1 de ago. de 2018 · The “beefy red” patch demonstrated the highest diagnostic validity (Youden index 0.84) and reliability (consistency 91.9% [95% CI: 87.3%–96.5%]), followed by the serum cobalamin levels and MCV.